News

Updates from VUS Genetics — company news, events, and publications.

News & press releases

Latest from VUS Genetics

Press Release·May 28, 2026
SickKids and VUS Genetics Announce geneSlice^™ Collaboration
Exclusive license of geneSlice^™ supports ongoing efforts to improve how genomic data informs care decisions.Read more

Events

Where to find us

bio:cap europe
June 9–11, 2026 — CityCube, Messe Berlin, Germany
International Life Science and AI Investival connecting global investors, founders, and industry leaders through keynotes, curated matchmaking, and pitch opportunities.Event site
Dutch Biotech Event 2026
June 12, 2026 — InnStyle, Maarssen, Netherlands
Annual gathering for biotech professionals featuring keynote speakers who bridge life sciences and entrepreneurship, with interactive workshops and networking.Event site

Publications

Selected publications

From our team and advisors — demonstrating the variant-classification approach our platform builds on.

Team publications

Mathis N, Allam A, Tálas A, …, Schep R, …, Schwank G.
Machine learning prediction of prime editing efficiency across diverse chromatin contexts.
Nat Biotechnol. 2025;43(5):712–719.PMID: 38907037
Schep R, Trauernicht M, Vergara X, …, van Steensel B.
Chromatin context-dependent effects of epigenetic drugs on CRISPR-Cas9 editing.
Nucleic Acids Res. 2024;52(15):8815–8832.PMID: 38953163
van Gemert F, Drakaki A, Morales Lozano I, …, Te Riele H.
ADARp150 counteracts whole genome duplication.
Nucleic Acids Res. 2024;52(17):10370–10384.PMID: 39189458
Muniesa-Vargas A, Davó-Martínez C, Ribeiro-Silva C, et al.
Persistent TFIIH binding to non-excised DNA damage causes cell and developmental failure.
Nat Commun. 2024.PMID: 38664429
Schep R, Brinkman EK, Leemans C, …, van Steensel B.
Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance.
Mol Cell. 2021;81(10):2216–2230.PMID: 33848455

Foundational work

Earlier methodological work from team members and founders that pre-dates the geneSlice^™ platform but demonstrates the variant-classification approach.

Ivakine et al, 2022.
Saturation mutagenesis of NPC1 and BRCA2 for functional variant classification.
PMID: 35190686
Pettitt et al, 2018.
Mutational scanning for compound–target interaction in DDR drug development.
PMID: 29748565